Cart
sales@molnova.com
Home - Products - GPCR/G Protein - mGluR - Decoglurant (RO4995819)

Decoglurant (RO4995819)

CAS No. 911115-16-7

Decoglurant (RO4995819) ( RO4995819 )

Catalog No. M21765 CAS No. 911115-16-7

Decoglurant (RO4995819) is a negative allosteric modulator of?mGluR2?and?mGluR3. Decoglurant is developed as an antidepressant.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 147 In Stock
5MG 222 In Stock
10MG 357 In Stock
25MG 597 In Stock
50MG 851 In Stock
100MG 1152 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Decoglurant (RO4995819)
  • Note
    Research use only, not for human use.
  • Brief Description
    Decoglurant (RO4995819) is a negative allosteric modulator of?mGluR2?and?mGluR3. Decoglurant is developed as an antidepressant.
  • Description
    Decoglurant (RO4995819) is a negative allosteric modulator of?mGluR2?and?mGluR3. Decoglurant is developed as an antidepressant.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    RO4995819
  • Pathway
    GPCR/G Protein
  • Target
    mGluR
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    911115-16-7
  • Formula Weight
    447.34
  • Molecular Formula
    C??H??F?N?
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 250 mg/mL (558.86 mM; Need ultrasonic)
  • SMILES
    NC1=NC=C(C#CC2=C3N=C(C4=CC=C(C(F)(F)F)C=C4)C=C(C(F)(F)F)N3N=C2)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wilkinson ST, et al. A new generation of antidepressants: an update on the pharmaceutical pipeline for novel and rapid-acting therapeutics in mood disorders based on glutamate/GABA neurotransmitter systems. Drug Discov Today. 2019 Feb;24(2):606-615.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • LY 2812223

    A highly potent, functionally selective mGlu2 receptor agonist with EC50 of 13.6 nM in GTPγS functional binding assay.

  • JNJ-40411813

    A novel potent positive allosteric modulator of mGlu2 with EC50 of 147 nM.

  • LY-354740

    A potent and selective group 2 mGluRs agonist with EC50s of 55 ± 17 nM; possesses no activity at iGluR or group 1 mGluR (>100 uM).

Sign In Join Free